After playing out a campaign with parallel Rex, I've come to report this card is still really bad. It has so many downsides for the chance of some kind of positive. 
- The untranslated version still costs 3 resources to play, still takes up a hand slot, and unless you're parallel Rex with an Analysis in hand, it's one of the more difficult unlocks to get while also having lasting negative effects via curses in the bag. 
 
- You have to spend 4xp on it, or 8xp if you're going for the set, which if you're going to the trouble of doing the side-quest, you're probably going for the set. If you're parallel Rex, you can at least take Shrewd Analysis and cheat the upgrade because it's the only viable upgrade. 
 
- The Grimoire becomes less and less worth drawing the further you get into a scenario because you'll have less and less time to draw curses and therefore the value you get from the Grimoire becomes worse and worse. 
 
- If you play the Grimoire, you're down 3 resources and an action. Another major downside is it's a large drop to do nothing. You see no immediate benefits. So you have to resolve 4 curses and play two insights for the Grimoire to start looking like it's worth it. At that point you'll be down one resource but up one action. 3 insights played is where you can actually say the Grimoire was definitely worth playing, but for that to happen, you have to individually resolve 6 curses, and have drawn into three insights which you held onto this whole time. 
 
- The fact you have to hold onto insights is another major downside. You might have the Grimoire in play with 0 charges, but you're free now to do a big activation which includes some insights in your hand. Is it really worth it to hold onto them and take the chance you'll be free later to do the same big activation? 
 
Finally, you want to take the Grimoire because you want to save resources and actions on insights. At least in the case of parallel Rex who seems to be a major contender for the Grimoire...
- 14.5/45 possible insights are already 0 resources (I counted 1/2 if one upgrade was 0 but another wasn't. There were 3). 
 
- 14/45 possible insights are already fast. 
 
So you get a lot of overlap where you actually aren't getting the full benefit of the Grimoire's +1 resource, +1 action effect, meaning you may have to realistically play 4-5 insights for it to actually be worth it! You might say, "Oh, well I'll just spec my deck so I'm always saving on both," but there are so many 0 cost and/or fast insights that you'd just be kneecapping yourself by limiting your options at that point in order to make the Grimoire feel not terrible.