Rita's signature will usually just be committed to a skill test, but it does have some niche uses that synergize with cards she's already likely to be playing. It also sometimes just saves an action by fulfilling the same role as Taunt.
Cards that incidentally evade like Cheap Shot, Breaking and Entering, Sweeping Kick, or Stunning Blow make this a way to turn what would usually be wasted evades into extra damage, by effectively giving her the same effect as her Elder Sign for the turn.
This is especially worth it if you play this after you've already drawn the Elder Sign that turn or during the Mythos phase. In that case it turns each evade into a free 2 damage. Rita does also have Ace in the Hole which could add up to a lot of damage in one turn.
Finally, this can turn Fire Extinguisher into a mini-dynamite.